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Are You Frustrated, Stressed or Worried About Safely Lightening, Whitening, Repairing & Rejuvenating Your Skin?
(Published on September 14, 2018)
Glutathione is Packed with Great Benefits:
- Powerful antioxidant
- Reduces stress
- Reduces cell damage in the liver
- Helps fight against autoimmune disease
- Reduces symptoms of Parkinson's disease
- Formulated by Celebrity Dermatologist
- Proven safe and affective in numerous clinical studies
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**DISCLAIMER: THE STARTER KIT IS ONLY AVAILABLE WHILE SUPPLIES LAST. THIS AD DOES NOT GUARANTEE AVAILABILITY!**
Glutathione Clinical Study
Previous studies showed that supplementation of reduced form of glutathione (GSH, 500 mg/d) has a skin-lightening efficacy in humans. This study was designed to evaluate the influences of both GSH and oxidized form (GSSG), at doses lower than 500 mg/d, on improving skin properties.
Patients and Methods
A randomized, double-blind, placebo-controlled, parallel, three-arm study was conducted. Healthy female subjects were equally randomized into three groups and took GSH (250 mg/d), GSSG (250 mg/d), or placebo orally for 12 weeks. At each visit at baseline and for 12 weeks, skin features including melanin index, wrinkles, and other relevant biophysical properties were measured. Blood samples were collected for safety monitoring.
Results
In generalized estimating equation analyses, melanin index and ultraviolet spots of all sites including face and arm when given GSH and GSSG tended to be lower than placebo. At some sites evaluated, subjects who received GSH showed a significant reduction in wrinkles compared with those taking placebo. A tendency toward increased skin elasticity was observed in GSH and GSSG compared with placebo. There were no serious adverse effects throughout the study.
Conclusion
We showed that oral glutathione, 250 mg/d, in both reduced and oxidized forms effectively influences skin properties. Overall, glutathione in both forms are well tolerated.
Glutathione is regarded as food or health supplements in several countries including the US,Philippines, Malaysia, Taiwan, and Thailand, Our group previously reported that oral GSH administration (500 mg/d) resulted in lightening of skin color, when given for 4 weeks. The main objective of this study was to find out whether glutathione, in the reduced and oxidized forms, maintains its skin-lightening efficacy when given at a dose of 250 mg/d for 12 weeks.
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